Vezse, Panna; Benda, Bianka; Fekete, Andras; Golcs, Adam; Toth, Tunde; Huszthy, Peter published an article in 2022. The article was titled 《Covalently Immobilizable Tris(Pyridino)-Crown Ether for Separation of Amines Based on Their Degree of Substitution》, and you may find the article in Molecules.Application of 1195-59-1 The information in the text is summarized as follows:
A great number of biol. active compounds contain at least one amine function. Appropriate selectivity can only be accomplished in a few cases upon the substitution of these groups, thus functionalization of amines generally results in a mixture of them. The separation of these derivatives with very similar characteristics can only be performed on a preparative scale or by applying pre-optimized HPLC methods. A tris(pyridino)-crown ether was designed and synthesized for overcoming these limitations at a mol. level. It is demonstrated, that this selector mol. is able to distinguish protonated primary, secondary and tertiary amines by the formation of reversible complexes with different stabilities. This degree of substitution-specific mol. recognition of amines opens the door to develop separation processes primarily focusing on the purification of biol. active compounds in a nanomolar scale. The experimental process involved the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Application of 1195-59-1)
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Application of 1195-59-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts