《Catalyst-Controlled Chemodivergent Synthesis of Spirochromans from Diarylideneacetones and Organoboronic Acids》 was written by Liu, Na; Zhu, Wanjiang; Yao, Jian; Yin, Long; Lu, Tao; Dou, Xiaowei. Quality Control of 2-Hydroxyphenylboronic acid And the article was included in ACS Catalysis in 2020. The article conveys some information:
A chemodivergent synthesis of two series of spirochromans depending on the catalytic system was developed. Starting from diarylideneacetones and organoboronic acids, asym. rhodium catalysis led to the enantioselective synthesis of 4,4′-disubstituted 2,2′-spirobichromans I [R = H, 8(and 8′)-Br, 6(and 6′)-Cl, etc.; Ar = Ph, 3-thienyl, 4-F3CC6H4, etc.], while acid catalysis led to the formation of 4-substituted spirochroman-2,2′-chromenes such as II [R = 6(and 6′)-MeO; R1 = (E)-styryl, 2-furyl, 3-F-4-MeOC6H3, etc.]. A plausible mechanism of the chemodivergent synthesis was proposed. In addition to this study using 2-Hydroxyphenylboronic acid, there are many other studies that have used 2-Hydroxyphenylboronic acid(cas: 89466-08-0Quality Control of 2-Hydroxyphenylboronic acid) was used in this study.
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Quality Control of 2-Hydroxyphenylboronic acid
Referemce:
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