Quality Control of Oxetan-3-olIn 2022 ,《Trifluoromethyl Selenoxides: Electrophilic Reagents for C-H Trifluoromethylselenolation of (Hetero)Arene》 was published in Organic Letters. The article was written by Li, Yang; Wang, Yanan; Ye, Zhegao; Zhang, Shangbiao; Ye, Xiaodong; Yuan, Zheliang. The article contains the following contents:
Herein, designed and synthesized the new electrophilic trifluoromethylselenolation reagents, trifluoromethyl selenoxides I [X = H, CF3, CN], which were easy to prepare and easy-to-handle and were not moisture or air sensitive. The selenoxides are successfully applied to metal-free C-H trifluoromethylselenolation of a series of (hetero)arenes to gave ((trifluoromethyl)selanyl)aryl ArSeCF3 [Ar = 4-HOC6H4, 1H-indol-3-yl, (5-methoxycarbonyl-1H-pyrrol-3-yl), etc.]. After reading the article, we found that the author used Oxetan-3-ol(cas: 7748-36-9Quality Control of Oxetan-3-ol)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Quality Control of Oxetan-3-ol
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