In 2022,Zhong, Shuting; Fang, Xianfu; Wang, Yiting; Zhang, Gong; Li, Yangfeng; Li, Yizhou published an article in Organic Letters. The title of the article was ãDNA-compatible diversification of indole Ï-activated alcohols via a direct dehydrative coupling strategyã?Application of 7748-36-9 The author mentioned the following in the article:
Indole-based diversification is highly desired in the DNA-encoded chem. library construction. Herein, we present a general strategy for on-DNA synthesis of diverse C3-functionalized indole derivatives via indole π-activated alc. formation followed by direct dehydrative coupling. Highly efficient bond linkages of C-C, C-N, and C-S were achieved to fuse building blocks that are widely com. available. DNA-encoding compatibility of the method has been further demonstrated to pave an avenue for application in constructing indole-focused three-dimensional libraries. In the part of experimental materials, we found many familiar compounds, such as Oxetan-3-ol(cas: 7748-36-9Application of 7748-36-9)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Application of 7748-36-9
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