Morack, Tobias; Onneken, Carina; Nakakohara, Hiroshi; Mueck-Lichtenfeld, Christian; Gilmour, Ryan published their research in ACS Catalysis in 2021. The article was titled ãEnantiodivergent Prenylation via Deconjugative Isomerizationã?Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The article contains the following contents:
A light-enabled deconjugative isomerization of activated alkenes containing an aryl ketone antenna, e.g., (E)-2,4-dimethyl-1-phenylpent-2-en-1-one is disclosed through sequential geometric isomerization/hydrogen atom transfer (HAT)/protonation. Detailed mechanistic analyses have guided the development of an enantioselective variant of this atom economical process (up to 99% and 95:5 e.r.). Importantly, the chiral pool quasi-enantiomers quinine and quinidine serve as effective catalysts, thereby rendering this addition to the chiral drug discovery module portfolio enantiodivergent. In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol) was used in this study.
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts