ãCu-catalyzed C-C bond formation of vinylidene cyclopropanes with carbon nucleophilesã?was written by Chen, Jichao; Gao, Shang; Chen, Ming. Synthetic Route of C13H26B2O4This research focused onvinylidene cyclopropane alkynylboronate regioselective nucleophilic addition reaction; dialkynyl ester preparation. The article conveys some information:
The development of Cu-catalyzed addition of carbon nucleophiles to vinylidene cyclopropanes was reported. The reactions with 1,1-bisborylmethane provided homopropargylic boronate products by forming a C-C bond at the terminal carbon atom of the allene moiety of vinylidene cyclopropanes. Alkynyl boronates are also suitable nucleophile precursors in reactions with vinylidene cyclopropanes, and skipped diynes were obtained in high yields. In addition, the Cu-enolate generated from the initial addition of nucleophilic copper species to vinylidene cyclopropanes can be intercepted by an external electrophile. As such, vinylidene cyclopropane serves as a linchpin to connect a nucleophile and an electrophile by forming two carbon-carbon bonds sequentially. After reading the article, we found that the author used Bis[(pinacolato)boryl]methane(cas: 78782-17-9Synthetic Route of C13H26B2O4)
Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.Synthetic Route of C13H26B2O4 Organoboron compounds have been a cornerstone of synthetic transformations for decades. Areas such as boron-containing catalysts, metalate chemistry, photoredox methods, and boryl anions have brought significant new developments in understanding and provided new reactivity upon.
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