Srivastava, Abhishek; Sharma, Vivek; Singh, Vinay Kumar; Srivastava, Krishna published an article in 2022, the title of the article was A simple and sensitive inhibitory kinetic method for the carbocisteine determination.COA of Formula: C12H24O11 And the article contains the following content:
A fast, reproducible, and sensitive method is proposed for the kinetic determination of carbocisteine (CCys). The method depends on the inhibitory property of carbocisteine, which reduces the Hg2+ catalyzed substitution rate of cyanide from [Ru(CN)6]4- with N-R-salt (1-Nitroso-2-naphthol-3,6-disulfonic acid disodium salt) via forming a stable complex with Hg2+. Spectrophotometric measurements were carried out by recording the absorbance at 525 nm (λmax of [Ru(CN)5 Nitroso-R-Salt]3- complex) at a fixed time of 10 and 15 min under the optimized reaction conditions with [N-R-salt] = 4.5 x 10-4 M, I = 0.05 M (KNO3), Temp = 45.0 ± 0.2°C, pH = 7.0 ± 0.03, [Hg2+] = 8.0 x 10-5 M and [Ru(CN)64-] = 4.25 x 10-5 M. With the proposed method, CCys can be determined quant. down to 3.0 x 10-6 M. This methodol. can be effectively used for the rapid quant. estimation of CCys in the pharmaceutical samples with good accuracy and reproducibility. The addition of common excipients in pharmaceuticals even up to 1000 times with [CCys] does not interfere significantly in the estimation of CCys. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).COA of Formula: C12H24O11
The Article related to carbocisteine inhibitory kinetic method, Pharmaceutical Analysis: General and other aspects.COA of Formula: C12H24O11
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