On June 21, 2007, Vanotti, Ermes; Menichincheri, Maria; Orsini, Paolo; Scolaro, Alessandra; Varasi, Mario published a patent.Electric Literature of 87674-15-5 The title of the patent was Preparation of N-substituted pyrrolopyridinones active as kinase inhibitors. And the patent contained the following:
The title compounds I [A = pyridin-4-yl, 3-fluoropyridin-4-yl, 2-aminopyrimidin-4-yl; R1 = H, halo, alkyl; R2 = alkyl, cycloalkyl, aryl, etc.; R3-R6 = H, alkyl, aryl, etc.], useful as Cdk2 or Cdc7 antagonists, were prepared Thus, reacting tert-Bu 2-(2-aminopyrimidin-4-yl)-4-oxo-1,4,6,7-tetrahydropyrrolo[3,2-c]pyridine-5-carboxylate with 1-bromo-2-fluoroethane followed by deprotection afforded 2-(2-aminopyrimidin-4-yl)-1-(2-fluoroethyl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one. Pharmaceutical composition comprising the compound I is disclosed. The experimental process involved the reaction of 1-(3-Fluoropyridin-4-yl)ethanol(cas: 87674-15-5).Electric Literature of 87674-15-5
The Article related to pyrrolopyridinone preparation cdk2 cdc7 protein kinase inhibitor antagonist, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Electric Literature of 87674-15-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts