On August 4, 2022, Li, Ao; Chen, Yile; Cao, Guoqing published a patent.COA of Formula: C6H10O3 The title of the patent was Toxin molecule suitable for antibody-drug conjugate. And the patent contained the following:
The present invention provides a toxin mol. suitable for an antibody-drug conjugate. In particular, the present invention provides a compound represented by structure I (X = H, OH, NH2, NHR0; Y = (CR1R2)n; Z = bond, carbonyl, thiocarbonyl, sulfonyl, etc.; R0 = C1-8 alkyl, haloalkyl, alkoxy, etc.; R1,R2 = H, D, halo, alkyl, etc.; R3,R4 = halo, C1-8 alkyl, haloalkyl, etc.; n = 0-3 integers). The claimed compound is prepared via multiple steps (procedure given). The prepared compound can be used in the preparation of a pharmaceutical composition for treating diseases associated with tumor cell proliferation. The experimental process involved the reaction of 3-Cyclopropyl-2-hydroxypropanoic acid(cas: 1599840-16-0).COA of Formula: C6H10O3
The Article related to toxin mol preparation antibody drug conjugate antitumor agent, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.COA of Formula: C6H10O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts