Chung, Sheng-Hsuan; Lin, Ting-Ju; Hu, Qian-Yu; Tsai, Chia-Hua; Pan, Po-Shen published an article in 2013, the title of the article was Synthesis of boron-containing primary amines.Product Details of 1333264-06-4 And the article contains the following content:
B-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the 1st step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters, e.g., p-(pinB)C6H4CH2NH2 (Bpin = 4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl), in good to excellent yields. These compounds were further used to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) under microwave irradiation The prepared Ugi-4CR boronate esters were then successfully converted to the corresponding boronic acids. Finally, the peptoid structures were successfully modified by cross-coupling to aryl/heteroaryl chlorides via a Pd-mediated Suzuki coupling reaction to yield the corresponding derivatives in moderate to good yields. The experimental process involved the reaction of [4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol(cas: 1333264-06-4).Product Details of 1333264-06-4
The Article related to aminomethylphenyl boronate ester preparation ugi four component reaction, peptoid boronate ester preparation suzuki coupling aryl heteroaryl chloride, hydroxymethylphenyl boronate ester preparation condensation phthalimide salt and other aspects.Product Details of 1333264-06-4
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