Xiong, Kangning team published research in Chemical Engineering Research and Design in 2020 | 24034-73-9

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 24034-73-9, formula is C20H34O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Xiong, Kangning;Chen, Yun research published 《 Supercritical carbon dioxide extraction of essential oil from tangerine peel: Experimental optimization and kinetics modelling》, the research content is summarized as follows. In this work, tangerine peel oil extraction is carried out by applying the supercritical carbon dioxide (scCO2) extraction The effect of extraction parameters on extraction yield was discussed, at particle size of 0.2-1.0mm, temperature of 35-55°C, pressure of 10-30MPa and extraction time of 0-180min. And the response surface methodol. (RSM) with a Box-Behnken Design (BBD) was applied to obtain the optimal extraction conditions. Based on this investigation, it is indicated that the optimized operation conditions for tangerine peel oil extraction was temperature 45°C, pressure 14MPa and extraction time 147min, and the largest exptl. yield of tangerine peel oil was 1.34%. Moreover, a gas chromatog.-mass spectrometry (GC-MS) anal. was used to determine the chem. composition of tangerine peel oil. The major compounds found in the tangerine peel oil were n-hexadecanoic acid (14.62%), linoleic acid (32.3%) and oleic acid (20.42%). Finally, two kinetic models were used to correlate the exptl. results, and the parameters in both models have been optimized by simulating annealing (SA) algorithm. The results show that the overall average absolute relative deviation (AARD) values of model I and model II are 3.42% and 2.76%, resp. The AARD value of model II is smaller and the application of model II is more extensive. The extraction parameters optimization, chem. composition anal. and kinetics modeling can provide theor. basis for industrialization of extraction of tangerine peel oil.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts