Nallagangula, Madhu; Sujatha, Chandragiri; Bhat, Venugopal T.; Namitharan, Kayambu published the artcile< A nanoscale iron catalyst for heterogeneous direct N- and C-alkylations of anilines and ketones using alcohols under hydrogen autotransfer conditions>, Synthetic Route of 5344-90-1, the main research area is aryl amine preparation; alc amine alkylation iron catalyst; preparation aryl ketone; acetophenone alc alkylation iron catalyst; quinoline preparation; amino benzyl alc Friedlander iron catalyst.
An efficient synthesis of amine and ketone derivatives RCH2NHR1 [R = n-pentyl, Ph, 4-OMe, etc.; R1 = Ph, 2-MeOC6H4, 2-pyridyl etc.] and R2CH2CH2C(O)R3 [R2 = Ph, 2-MeC6H4, 4-MeSC6H4, etc.; R3 = Ph, 4-MeC6H4, 4-EtOC6H4, etc.] was described via heterogeneous iron catalyzed direct N- and C-alkylation reactions of amines and acetophenones with alcs. under hydrogen autotransfer conditions. In addition, modified Friedlander synthesis of quinolines I [R4 = H, Me; R5 = Ph, 4-EtC6H4, 4-FC6H4, etc.] was demonstrated from 2-amino benzyl alcs. and acetophenones. A hydrogen autotransfer mechanism was found to operate in these reactions by deuterium labeling studies.
Chemical Communications (Cambridge, United Kingdom) published new progress about Alkylation. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts