Hu, Wei; Li, Changzhu; Dai, Jinming; Cui, Haiying; Lin, Lin published the artcile< Antibacterial activity and mechanism of Litsea cubeba essential oil against methicillin-resistant Staphylococcus aureus (MRSA)>, HPLC of Formula: 78-70-6, the main research area is Litsea Staphylococcus essential oil antibacterial cell hexose monophosphate pathway.
Litsea cubeba essential oil (LC-EO), one of the natural essential oils, could gradually replace chem. synthesis food additive in food industry due to its good antimicrobial activity. However, the antibacterial mechanism of the LC-EO is uncertain. This study took methicillin-resistant staphylococcus aureus (MRSA) as the research object to exposit its antibacterial mechanism. Research findings indicated the destructive effect of LC-EO on MRSA cell membrane, leading to intracellular biol. macromols. leakage. Whats more, the Hexose Monophophate Pathway (HMP) and its key enzyme (glucose-6-phosphate dehydrogenase) activity of MRSA were also inhibited after LC-EO treatment. Finally, the UV absorption spectroscopy result revealed that the key component of LC-EO (citral) could react with DNA in the form of chimera.
Industrial Crops and Products published new progress about Antibacterial agents. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, HPLC of Formula: 78-70-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts