Hedbom, Christina’s team published research in Acta Pharmaceutica Suecica in 1972 | 22620-34-4

Acta Pharmaceutica Suecica published new progress about 22620-34-4. 22620-34-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H6ClNO, HPLC of Formula: 22620-34-4.

Hedbom, Christina; Helgstrand, Erik; Misiorny, Alfons; Stjernstrom, Nils E.; Westin, Gertrud published the artcile< Potential hypolipidemic agents. II. Preparation of 5-halo-3-pyridylmethanols>, HPLC of Formula: 22620-34-4, the main research area is fluoronicotinate; nicotinate halo reduction; halopyridinemathanol; pyridine methanol halo.

The 3-pyridinemethanols (I, R = Br, Cl, F) were prepared in 40, 52, and 73% yields resp. by NaBH4 or KBH4 reduction of the corresponding Et halonicotinates. 5-Fluoronicotinic acid was prepared in 48% yield by diazotizing 5-aminonicotinic acid in HBF4-THF-H2O and decomposing the resulting salt in refluxing ligroine.

Acta Pharmaceutica Suecica published new progress about 22620-34-4. 22620-34-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H6ClNO, HPLC of Formula: 22620-34-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts