Adding a certain compound to certain chemical reactions, such as: 41570-61-0, 2-(tert-Butylamino)-1-(2-chlorophenyl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 41570-61-0, blongs to alcohols-buliding-blocks compound. HPLC of Formula: C12H18ClNO
Tulobuterol (1.00 g) and Boc-beta-alanine (0.99 g) were dissolved in dichloromethane (10 mL). After cooling to 0 C., N,N-dimethylaminopyridine (161.3 mg) and water soluble carbodiimide (1.11 g) were added thereto followed by stirring for 3 hours at room temperature. After confirming the disappearance of the reacting materials by thin layer chromatography, a saturated aqueous solution of ammonium chloride was added to terminate the reaction. After dilution with ethyl acetate, the organic layer was washed with a saturated aqueous solution of ammonium chloride, a saturated aqueous solution of sodium hydrogen carbonate, and saturated brine. After drying over magnesium sulfate anhydrous, it was filtered and the solvent was distilled off under reduced pressure to obtain the desired compound 42 (1.71 g, 98%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,41570-61-0, its application will become more common.
Reference:
Patent; SEIKAGAKU CORPORATION; Sato, Tomoya; Takeuchi, Hisayuki; Zuinen, Ryoji; (39 pag.)US2016/158369; (2016); A1;,
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