Adding a certain compound to certain chemical reactions, such as: 13826-35-2, (3-Phenoxyphenyl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: (3-Phenoxyphenyl)methanol, blongs to alcohols-buliding-blocks compound. name: (3-Phenoxyphenyl)methanol
In 1000ml four-necked flask (equipped with lye absorption device) was added 500g of dichloromethane, stirring was started to continue the addition of 100g m-phenoxybenzyl alcohol and 30g of tetramethylethylenediamine.Cooling to -35 C, began to drop prepared 70g of thionyl chloride and methylene chloride solution. During the dropwise addition temperature was controlled at -45 C. After the addition was completed at -45 heat 4h. After that, the reaction solution was pouredInto 1000ml of water, stirring, phase separation, the organic phase were washed with 600ml of water, phase separation. The organic phase was desolvated to 100 C under atmospheric pressure and the solvent methylene chloride was recovered. Then decompression (vacuum degree 0.097MP) fractionation, intermediates chloroacenesulfonic acid phenoxybenzyl 127g. Purity 99%, yield 90%.
The synthetic route of 13826-35-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Tianjin Jinlvbao Pesticide To Make Co., Ltd.; Wang Baojun; Cui Weizhong; Lu Sen; (8 pag.)CN106495994; (2017); A;,
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