Adding a certain compound to certain chemical reactions, such as: 2516-33-8, Cyclopropylmethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of Cyclopropylmethanol, blongs to alcohols-buliding-blocks compound. Safety of Cyclopropylmethanol
To a 2 L flask was charged with cyclopropanemethanol (8A) (18 g, 250 mmol, 1 equiv), TEMPO (78 mg, 0.5 mmol) and CH2Cl2 (250 mL). The solution was cooled to 0 C, and a solution of KBr (2.99 g, 25 mmol, 0.1 equiv), NaHCO3 (52.5 g, 625 mmol, 2.5 equiv), and 10-13% NaOCl (150 mL, 313 mmol, 1.25 equiv) in H2O (80 mL) was then slowly added. After the resulting mixture was had been stirring at 0 C for 45 min, the two layers were separated. The aqueous layer was back extracted with CH2Cl2 (2 x 250 mL). The combined organic extracts were dried over MgSO4, filtered, and concentrated. The resulting residue was purified via shortpath distillation head under N2 (95-100 C) to give the corresponding aldehyde 8B (11. 02 g, 73%) as a colorless liquid.
The synthetic route of 2516-33-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Trost, Barry M.; Nguyen, Hien M.; Koradin, Christopher; Tetrahedron Letters; vol. 52; 17; (2011); p. 2033 – 2036;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts