Electric Literature of 20605-01-0, Adding some certain compound to certain chemical reactions, such as: 20605-01-0, name is Diethyl 2,2-bis(hydroxymethyl)malonate,molecular formula is C9H16O6, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 20605-01-0.
EXAMPLE 6 Diethyl 2-isopropyl-1,3-dioxane-5,5-dicarboxylate A mixture of 165.0 g of diethyl bis(hydroxymethyl)malonate, 83.4 g of trimethylorthoformate and 0.6 g of sodium hydrogen sulfate was heated, with stirring, to 50 C. for 30 minutes and then to 60 C. for 90 minutes. Over a period of 45 minutes, 81.0 g of isobutyraldehyde were then added gradually, the internal temperature being kept to 60 C. by gentle cooling. The low-boiling components formed were distilled off up to a bottom temperature of 120 C., and 1.0 g of sodium carbonate was then added to neutralize the catalyst. Subsequent distillation in an oil pump vacuum afforded 168.2 g of colorless target product (82% of the theoretical yield, based on the diethyl bis(hydroxymethyl)malonate used) with a boiling point of 110 C./1 mm. The purity, determined by gas chromatography, was 98 FID percent by area.
According to the analysis of related databases, 20605-01-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Huels Aktiengesellschaft; US5932747; (1999); A;,
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