As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 13826-35-2, name is (3-Phenoxyphenyl)methanol, molecular formula is C13H12O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Formula: C13H12O2
first step: A solution of IV-1 (3-phenoxyphenyl) methanol (0.5 g, 2.5 mmol) obtained in the previous step was dissolved in 30 ml of dichloromethane, and 20 ml of SOCl2 was added to 1 ml of DMF as a catalyst,25 C for 2 hours, After the TLC detection reaction was complete, the reaction solution was evaporated under reduced pressure to give excess SOCl2 to give a pale yellow oil IV-2 which was used directly in the next step.
With the rapid development of chemical substances, we look forward to future research findings about 13826-35-2.
Reference:
Patent; China Pharmaceutical University; Huang Wenlong; Qian Hai; Liu Chunxia; Li Zheng; Yang Jianyong; Bi Xinzhou; Cai Xingguang; (20 pag.)CN107162913; (2017); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts