Application of 504-63-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 504-63-2, name is 1,3-Propanediol, molecular formula is C3H8O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
(1) Put 440kg of 1,3-propanediol, 600kg of hydrochloric acid, and 3kg of benzenesulfonic acid into a 2000L glass-lined kettle with a stirring and reflux condensing device, heat up to 90 C with stirring, and keep the reaction warm;(2) After holding for 3 hours, lower the temperature of the kettle to 50 C, then put 460kg of hydrochloric acid into the kettle, continue to warm to 90 C and keep the reaction for 10 hours. The temperature of the kettle is sampled for GC analysis. When the content reaches 80%, the feed liquid is poured into the distillation kettle, and 150 kg of toluene is poured into the distillation kettle to carry out the reaction of heating and refluxing with water;(3) After the reaction with water is completed, the temperature of the kettle is reduced to room temperature, and sodium bicarbonate is added to neutralize the oil phase in the kettle to neutrality, and the salt formed by the neutralization and excess sodium bicarbonate are filtered;(4) The filtered oil phase is pumped into the rectification kettle, and the solvent toluene is concentrated under normal pressure. After the toluene is collected, the product is rectified by high vacuum. The rectified fraction is put into the reaction kettle to continue the reaction.The content detected by GC gas chromatography was 99.3%, and the product yield was 96%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 504-63-2, 1,3-Propanediol.
Reference:
Patent; Zouping Mingxing Chemical Co., Ltd.; Chen Qiang; Zhang Peng; Zhang Junling; Cao Xinming; Sun Fantong; Wang Tao; Du Xiaoyang; (6 pag.)CN110668918; (2020); A;,
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