Adding a certain compound to certain chemical reactions, such as: 4249-72-3, 2-Phenoxy-1-phenylethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C14H14O2, blongs to alcohols-buliding-blocks compound. Formula: C14H14O2
2-phenoxy-1-phenylethan-1-ol ((50 gm, 0.236 mmol), TEMPO (7.3 mg, 0.047 mmol), CuCl (4.6 mg, 0.047 mmol), NMI (7.7 mg, 0.94 mmol), bpy (7.3 mg, 0.047 mmol) and MeCN (.93 mL, 0.25 M of substrate) stirred under an air atmosphere (1 atm) at 25 C for 20 h. The reaction mixture was quenched with 1 N HCl and product were extracted with dichloromethane. The organic layer was washed with the water, dried over MgSO4 and concentrated under vacuum. The products were separated by silica-gel column chromatography (EtOAc:hexane 1:20) to produce 2-phenoxy-1-phenylethan-1-ol (48 mg, 0.224 mmol, 95%), 2-phenoxy-1-phenylethan-1-one (2.5 mg, 0.012 mmol, 5%).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,4249-72-3, 2-Phenoxy-1-phenylethanol, and friends who are interested can also refer to it.
Reference:
Article; Patil, Nikhil D.; Yan, Ning; Tetrahedron Letters; vol. 57; 27-28; (2016); p. 3024 – 3028;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts