Extended knowledge of (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-ol

According to the analysis of related databases, 106-28-5, the application of this compound in the production field has become more and more popular.

Electric Literature of 106-28-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 106-28-5, name is (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

General procedure: To a solution of geraniol (1b, 4.45 g, 28.8?mmol) in dichloromethane (15?ml) were added DMAP (175?mg, 1.43?mmol) and acetic anhydride (6.0?ml, 63?mmol) and the mixture was stirred at room temperature under nitrogen for 1 h. After addition of methanol (10?ml), the reaction mixture was further stirred for 1 h, diluted with diethyl ether, washed twice with aq. 4% sodium hydrogen carbonate, distilled water, and brine, and dried over sodium sulfate. The solvents were evaporated and the residue was purified with FCC (hexane:ethyl acetate?=?20:1) to give geranyl acetate (2b, 4.04?g, 20.6?mmol) in 71% yield:

According to the analysis of related databases, 106-28-5, the application of this compound in the production field has become more and more popular.

Reference:
Article; Tamiaki, Hitoshi; Nomura, Kota; Mizoguchi, Tadashi; Bioorganic and Medicinal Chemistry; vol. 25; 24; (2017); p. 6361 – 6370;,
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