Related Products of 61439-59-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 61439-59-6, name is 2-(4-(Benzyloxy)phenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows.
B) To a solution of 2- (4-BENZYLOXY-PHENYL)-ETHANOL (78.72g, 0. 34MOL) in methylene chloride (400MUT) is added triethylamine (67. 3MOI, 0. 44MOL, 1.4eq), then at 0¡ãC is added mesylchloride (34. 8MOI, 0. 44MOL, 1.3eq). The reaction mixture is stirred at 0¡ãC for 30 minutes and allowed to rise to RT. The reaction mixture is extracted with methylene chloride (2 x 300MIS, the combined organic layers are then washed with brine (2 x 300MI) and concentrated under vacuum; To a solution of 2- (4-BENZYLOXY-PHENYL)-ETHANOL (78.72g, 0. 34MOL) in methylene chloride (400MI) is added triethylamine (67. 3ml, 0. 44MOL, 1.4eq), then at 0¡ãC is added mesylchloride (34. 8RNL, 0. 44MOL, 1.3eq). The reaction mixture is stirred at 0¡ãC for 30 minutes and allowed to rise to room temperature. The reaction mixture is extracted with methylene chloride (2 x 300ml), the combined organic layers are then washed with brine (2 x 300ml) and concentrated under vacuum. To the crude product in solution in ethyl acetate 600ml) is added sodium iodide (67.2g, 0. 44MOL, 1.3eq) and the reaction mixture is stirred under reflux for 6 hours. After filtration, the organic layer is washed with brine (3 x 00ml), dried with NA2SO4, filtered and concentrated under vacuum. 1-Benzyloxy-4-(2-iodo-ethyl)-benzene is isolated after crystallization with diethyl ether (116. 5g, 86percent).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 61439-59-6, 2-(4-(Benzyloxy)phenyl)ethanol.
Reference:
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2005/21503; (2005); A1;,
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