Extracurricular laboratory: Synthetic route of 1454-85-9

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1454-85-9, Heptadecan-1-ol.

Reference of 1454-85-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1454-85-9, name is Heptadecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

To an ice-cold solution of heptadecanol (2.0 g, 7.8 mmole) in methylenechloride (20 rut) and TEA (3 rat, 20 rumole) was added the abovesuspension of acid chloride (9.3 mmole) in nethylene chloride (20 mL). After stirring for 10 ninutes at ice bath tenperature, the ice?bath was removed and stirring continued at room temperature for 4 h. The reaction mixture was then washed with water (2 x 8 mL) followed bybrine (10 mL), dried over anhydrous sodium sulfate, filtered and concentrated. The crude residue was purified by column chromatography using 5percent methanol in methylene chloride to give the pure required compound 17 (1.1 g, 27percent) as a off white solid, m.p.llo?112¡ã C. ?H NHR (CDC13) 5 0.87 (t, d, .1=7.2 Hz, 3H), 1.24 (m, 28H), 1.40?1.51 (m, 4H),1.60?1.79 (m, 2H), 2.55 (s,3H), 2.75 (m, 3H), 2.85?3.06 (m, 4H),3.60?3.85 (m,3H), 4.03(t, d, J=7.2 Hz, 2H), 4.88 (m,1H), 4.94(m,lH); ESMS:507 (H+H)

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1454-85-9, Heptadecan-1-ol.

Reference:
Patent; LIXTE BIOTECHNOLOGY, INC.; KOVACH, John, S.; JOHNSON, Francis; SAMUDRALA, Ramakrishna; GUPTA, Ramesh, C.; WO2015/73802; (2015); A1;,
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