Application of 261723-32-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 261723-32-4, name is (3-Bromo-2-fluorophenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
Pyridinium chlorochromate (22.3 g, 103 mmol, 1.91 eq) was dissolved in DCM (140 mL) and 4 Molecular Sieves (22.3 g) were added to the solution. The reaction mixture was stirred for 30 minutes. A solution of benzyl alcohol 40 (11 g, 54 mmol, 1 eq) in DCM (140 mL) was added dropwise over the course of 5 min. The orange reaction mixture immediately turned dark brown upon addition of alcohol. After stirring for 30 min, the reaction mixture was diluted with 70% Hexane/EtOAc solution (250 mL) and filtered through a plug of silica gel (150 g). The silica gel was washed with Hexane/EtOAc (500 mL), and concentrated in vacuo to afford 9.8 g of aldehyde 41 as a white solid. Yield 70% over 2 steps.
According to the analysis of related databases, 261723-32-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Infinity Discovery, Inc.; US2008/114167; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts