Related Products of 20017-67-8, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 20017-67-8, name is 3,3-Diphenyl-1-propanol. A new synthetic method of this compound is introduced below.
Methanesulfonyl chloride (2.16 g, 18.8 mmol) was slowly added to an ice-cooled solution of 3,3-diphenylpropan-1 -ol ( 4.0 g, 18.8 mmol) and thethylamine (5.7 g, 56.5 mmol) in dichloromethane (18 ml_). The mixture was then allowed to warm to room temperature and stirred overnight. It was then diluted with water and dichloromethane. The phases were separated and the aqueous phase was re- extracted twice with dichloromethane. The combined organic phases were dried over Na2SO4 and concentrated to dryness, providing the desired compound as a crude that was directly used without further purification.1H NMR (300 MHz, CDCI3) delta: 2.53 (m, 2H), 2.91 (s, 3H), 4.13-4.21 (m, 3H), 7.2- 7.35 (m, 10H).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,20017-67-8, its application will become more common.
Reference:
Patent; PALAU PHARMA, S. A.; CARCELLER GONZALEZ, Elena; VIRGILI BERNADO, Marina; WO2010/43633; (2010); A1;,
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