A new synthetic route of 56-81-5

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 56-81-5, Propane-1,2,3-triol, other downstream synthetic routes, hurry up and to see.

56-81-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 56-81-5, name is Propane-1,2,3-triol, molecular formula is C3H8O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: Diols and polyol reactants (100 mg) were allowed to react with benzoic anhydride (1.1 equiv) in acetonitrile (1 mL) at 40C for 8-12 h in the presence of TBAOBz (0.2 equiv). The reaction mixture was directly purified by flash column chromatography (hexanes/EtOAc=2:1 to 1:1), affording the pure selectively protected derivatives.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 56-81-5, Propane-1,2,3-triol, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Zhang, Xiaoling; Ren, Bo; Ge, Jiantao; Pei, Zhichao; Dong, Hai; Tetrahedron; vol. 72; 7; (2016); p. 1005 – 1010;,
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