Related Products of 4654-39-1, Adding some certain compound to certain chemical reactions, such as: 4654-39-1, name is 2-(4-Bromophenyl)ethanol,molecular formula is C8H9BrO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 4654-39-1.
3.0 g 2-(4-bromophenyl)ethanol (15 mmol) and 2.1 g imidazole (31 mmol) were dissolved in 20 mL dichloromethane. A solution of 2.3 g (tert-butyl)dimethylchlorosilane (15.5 mmol) dissolved in 20 mL dichloromethane was added and the mixture stirred overnight, forming a precipitate. The mixture was diluted with dichloromethane and washed three times with 4% w/v sodium carbonate solution, water and was dried over sodium sulphate. Evaporation and purification of the residue by chromatography (ethyl acetate-hexane gradient, 0:100 to 20:80) gave 3.6 g (76%) of [2-(4-bromophenyl)ethoxy](tert-butyl)dimethylsilane. 1H NMR (200 MHz, CHLOROFORM-d) ppm 7.42 (2 H, d, J=8.2 Hz), 7.11 (2 H, d, J=8.2 Hz), 3.80 (2 H, t, J=6.6 Hz), 2.79 (2 H, t, J=6.8 Hz), 0.89 (9 H, s), 0.01 (6 H, s)
According to the analysis of related databases, 4654-39-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Almirall, S.A.; EP2196465; (2010); A1;,
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