Synthesis of 1,3-Dicarbonyl Compounds using N-Cbz Amides as an Acyl Source under Transition-metal-free Conditions at Room Temperature was written by Singh, Shweta;Kandasamy, Jeyakumar. And the article was included in Asian Journal of Organic Chemistry in 2022.Synthetic Route of C10H20O This article mentions the following:
A wide range of functionalized N-Cbz amides underwent base-promoted C-C coupling reactions with enolizable esters, ketones and amides to afford 1,3-dicarbonyl compounds under mild conditions. The reactions proceeded at room temperature in the presence of LiHMDS in cyclopentyl Me ether (CPME). The desired β-ketoesters, β-keto amides and 1,3-diketones were obtained in good to excellent yields in a short reaction time. Broad substrate scope, functional group tolerance and metal-free conditions are the merits of the developed methodol. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Synthetic Route of C10H20O).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C10H20O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts