Synthesis, conformational studies and enantioselective homogeneous catalytic hydrogenation with CRC-PHOS, and some congeners was written by Comisso, G.;Sega, A.;Sunjic, V.;Lisini, A.. And the article was included in Croatica Chemica Acta in 1981.Name: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid This article mentions the following:
The lactone of (1S,3R)-1-hydroxy-1-diphenylphosphinomethyl-2,2,3-trimethylcyclopentane-3-carboxylic acid (I, CRC-PHOS), and (1R,3R)-bis(diphenylphosphinoxymethyl)-2,2,3-trimethylcyclopentane (II), were prepared starting from (+)-camphanic and (-)-isocamphoric acid, resp. Their complex salts [RhL2(NBD)]ClO4 (L = I, NBD = norbornadiene) and [RhL1(NBD)]ClO4 (L1 = II) were isolated and their catalytic and enantioselective ability tested on some model prochiral carboxylic acids. The asym. bias did not exceed 35% e.e. in either case. Attempts at preparation of the diphosphine congener of II as well as isolation of the phosphinite congener of I failed. NMR LIS study of the conformation in solution of I and model compounds III and IV revealed that I and III possess in their most stable conformations a dihedral angle ψ of 165°, whereas for IV two stable conformations with ψ 200° and 350° are found. These results indicate that bidentate binding of metal to heteroatom X (O, P) in the side chain, and to the tetrahedral O within lactone group is scarcely possible. In the experiment, the researchers used many compounds, for example, 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6Name: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid).
2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Name: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts