The synthesis of benzimidazoles via a recycled palladium catalyzed hydrogen transfer under mild conditions was written by Guan, Qianqian;Sun, Qi;Wen, Lixian;Zha, Zhenggen;Yang, Yu;Wang, Zhiyong. And the article was included in Organic & Biomolecular Chemistry in 2018.Quality Control of (2-Bromo-5-chlorophenyl)methanol This article mentions the following:
An efficient synthesis of benzimidazoles I [R1 = Me, Ph, 2-thienyl, etc.; R2 = H, Me, CF3; R3 = H, Me, Ph, 2-pyridyl, 3-Me-2-pyridyl] was developed via recycled palladium-catalyzed hydrogen-transfer reaction of N-substituted-2-nitroanilines and alcs. The reaction was carried out smoothly under mild conditions that afforded variety of benzimidazoles I with good to excellent yields. The palladium catalyst was recovered easily and reused six times with great catalytic activity. In the experiment, the researchers used many compounds, for example, (2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8Quality Control of (2-Bromo-5-chlorophenyl)methanol).
(2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (2-Bromo-5-chlorophenyl)methanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts