Iron-Catalyzed Borrowing Hydrogen β-C(sp3)-Methylation of Alcohols was written by Polidano, Kurt;Williams, Jonathan M. J.;Morrill, Louis C.. And the article was included in ACS Catalysis in 2019.Product Details of 2968-93-6 This article mentions the following:
Herein we report the iron-catalyzed β-C(sp3)-methylation of primary alcs. using methanol as a C1 building block. This borrowing hydrogen approach employs a well-defined bench-stable (cyclopentadienone)iron(0) carbonyl complex as precatalyst (5 mol %) and enables a diverse selection of substituted 2-arylethanols to undergo β-C(sp3)-methylation in good isolated yields (24 examples, 65% average yield). In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6Product Details of 2968-93-6).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 2968-93-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts