Studies on agents with vasodilator and β-blocking activities. II was written by Seki, Toshimi;Takezaki, Takayuki;Ohuchi, Rikio;Ohuyabu, Hiroshi;Tanimoto, Yoshitaka;Yamaguchi, Takashi;Saitoh, Morinobu;Ishimori, Tsutomu;Yasuda, Kikuo. And the article was included in Chemical & Pharmaceutical Bulletin in 1995.COA of Formula: C5H13NO This article mentions the following:
Phenoxypropanolamines having a hydrazinopyridazinyl moiety I (n = integer; X = O, S; R = H, alkyl, etc.) were synthesized. Their hypotensive and β-blocking activities were evaluated after i.v. administration of the compounds to anesthetized rats. Some of them exhibited both activities. In particular, I (R = 2-chloro; n = 1; X = O) is a candidate for clin. use due to its hypotensive activity, equal to that of hydralazine, and its β-blocking activity, 2.4-fold more potent than that of propranolol. In the experiment, the researchers used many compounds, for example, 3-Amino-3-methylbutan-1-ol (cas: 42514-50-1COA of Formula: C5H13NO).
3-Amino-3-methylbutan-1-ol (cas: 42514-50-1) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C5H13NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts