Whistler, Roy L. et al. published their research in Journal of the American Chemical Society in 1956 | CAS: 10030-85-0

Cacao polysaccharides was written by Whistler, Roy L.;Masak, Edward Jr.;Plunkett, R. A.. And the article was included in Journal of the American Chemical Society in 1956.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate This article mentions the following:

The husks of mature Caracas cacao fruits extracted with EtOH and Me₂CO, the residue heated 0.5 h. at 15 lb. pressure in an autoclave with H₂O (50 cc./g.) and filtered, the filtrate poured into 2 volumes 95% EtOH, and the precipitated H₂O-soluble polysaccharide (I) washed with EtOH and dried over CaCl₂ in a vacuum desiccator gave material, [α]_D²⁵ 114°, intrinsic viscosity 10.12, pH 1% solution 6.36, natural ash 8.2%, ash after dialysis 0.3%, containing 0.557% N. The seed shaken 2 h. at room temperature with H₂O, and the mucilaginous seed coat extracted in a similar manner gave the seed polysaccharide (II), [α]_D²⁵ 106°, intrinsic viscosity 6.73, pH 1% solution 6.85, ash natural 8.3%, ash after dialysis 0.2%, containing 3.68% N. Aqueous 1% I diluted at 25° with stirring with increments of absolute EtOH, the mixture stirred after addition of each increment 10 min. and centrifuged 10 min. at 804 times gravity, and the precipitates dried and weighed gave only in the range 54.5-62.0% by volume EtOH precipitates II precipitated under similar conditions within the range 64.8-70.0% EtOH. Aqueous 1% I precipitated in the same manner with 1.0M KCl gave a precipitate of 16.5% of the I by a total KCl molarity of 0.60; no precipitation of II occurred up to 0.83M KCl concentration Sep. samples of I hydrolyzed 8 h. at 100° with N H₂SO₄ or HCl, neutralized with BaCO₃ or Ag₂O, resp., and the hydrolyzate chromatographed on paper showed the presence of rhamnose (III), arabinose (IV), glucose (V), galactose (VI), and a slow moving spot. I (and II) gave a pos. test for P and neg. tests for urinic acid and sulfate. I hydrolyzed at 43° with 2% H₂SO₄, and 2-cc. aliquots withdrawn periodically, neutralized with BaCO₃, filtered, and chromatographed showed the following order of release of monosaccharides: IV 0.5 h., VI 1.5 h., mannose and phosphate 8 h., III 12 h. II gave similarly: IV 0.5 h., mannose 1.5 h., VI 5, III and phosphate 8 h. I hydrolyzed with 5% H₂SO₄ and in another case with 43% HCl, the resulting sugar sirup (3.8 g.) chromatographed with 18:3:1:4 EtOAc-AcOH-HCO₂H-H₂O on a cellulose column gave 246 mg. III [obtained from a thick aqueous sirup as α-L-III.H₂O, m. 89-90°, [α]_D²⁵ 8.3° (c 0.344, H₂O)], 86 mg. unknown pentose saccharide, 321 mg. IV plus a trace of xylose [α-benzyl-α-phenylhydrazone of IV, white plates, m. 173-4° (from 50% EtOH), [α]_D²⁵ -9.5° (c 0.23, CHCl₃)], 170 mg. D-mannose (VII), [α]_D²⁵ 20.6°(c 0.68, H₂O), 238 mg. VI plus a trace V [α-D-VI, m. 160-1° (from aqueous AcOH), [α]_D²⁵ 81.2° (equilibrium)]. The unknown pentose saccharide crystallized from MeOH melted at about 35°, resolidified at 60-70°, and melted again at about 190°. Aqueous 2% I and II hydrolyzed 8 h. at 100° by N H₂SO₄, neutralized with BaCO₃, and the hydrolyzate chromatographed on Whatman Number 1 paper for 40 h. with EtOAc-pyridine-H₂O (8:2:1) showed the following compositions (% given): I: 37.97 III, 13.27 IV, VII plus trace of V 9.98, VI 38.77. II: 36.29 III, 28.81 IV, VII plus trace of V 12.02, VI 22.86. H₂O-soluble polysaccharides were isolated from the pulp, the mucus seed cover, and the seed placenta in yields of 0.17, 0.10, and 0.01% of the dry fruit; hydrolysis of these polysaccharides gave the same monosaccharides as I and II; the placenta and mucus also contained traces of xylose in contrast to II. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts