Chemicals of concern in building materials: A high-throughput screening was written by Huang, Lei;Fantke, Peter;Ritscher, Amelie;Jolliet, Olivier. And the article was included in Journal of Hazardous Materials in 2022.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol) This article mentions the following:
Chems. used in building materials can be a major passive emission source indoors, associated with the deterioration of indoor environmental quality. This study aims to screen the various chems. used in building materials for potential near-field human exposures and related health risks, identifying chems. and products of concern to inform risk reduction efforts. We propose a mass balance-based and high-throughput suited model for predicting chem. emissions from building materials considering indoor sorption. Using this model, we performed a screening-level human exposure assessment for chems. in building materials, starting from product chem. composition data reported in the Pharos Building Products Database for the USA. Health risks and MAximum chem. Contents from High-Throughput Screening (MACHTS) were determined, combining exposure estimates with toxicity information. Exposures were estimated for > 300 unique chem.-product combinations from the Pharos databases, of which 73% (25%) had non-cancer (cancer) toxicity data available. We identified 55 substances as chems. of high concern, with actual chem. contents exceeding MACHTS by up to a factor 105, in particular diisocyanates and formaldehyde. This stresses the need for more refined investigations to select safer alternatives. This study serves as a suitable starting point for prioritizing chems./products and thus developing safer and more sustainable building materials. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)).
2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts