Metal-Free Synthesis of Alkenylazaarenes and 2-Aminoquinolines through Base-Mediated Aerobic Oxidative Dehydrogenation of Benzyl Alcohols was written by Dahatonde, Dipak J.;Ghosh, Aritra;Batra, Sanjay. And the article was included in European Journal of Organic Chemistry in 2021.Recommanded Product: (2,4-Dichlorophenyl)methanol This article mentions the following:
A metal-free, base-mediated, and atom-efficient oxidative dehydrogenative coupling of substituted phenylmethanols (benzyl alcs.) with Me azaarenes or phenylacetonitriles to afford substituted alkenylazaarenes or 2-aminoquinolines, resp. was described. CsOH. H2O was discovered to be the base of choice for obtaining optimal yields of the title compounds, although the reaction proceeded with KOH as well. The protocol that worked efficiently in the presence of air was amenable over broad range of substrates. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Recommanded Product: (2,4-Dichlorophenyl)methanol).
(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Recommanded Product: (2,4-Dichlorophenyl)methanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts