AuPt NPs with enhanced electrochemical oxidization activity for ratiometric electrochemical aptasensor was written by Zhao, Yuan;Yao, Jie;Wu, Zhenglong;Liu, Han;Zheng, Wangwang. And the article was included in Biosensors & Bioelectronics in 2022.COA of Formula: C4H10O3 This article mentions the following:
Strong and stable electrochem. beacons are critical for the achievement of sensitive and reliable electroanal. applications. In this work, the electrochem. oxidation performance of AuPt NPs was studied and firstly found to be largely enhanced under light illumination. Plasmonic AuPt NPs collected light energy after local surface plasmon resonance (LSPR) excitation and generated much more holes to participate in the electrochem. oxidation process of Pt0 in AuPt NPs. AuPt NPs with the electrochem. oxidation peak at around -0.7 V were utilized as detection probes for the fabrication of ratiometric electrochem. aptasensor, by introducing Co-MOF/Fe3O4/Ag nanosheets (NSs) with the electrochem. oxidation peak at 0.1 V as reference beacons. The aptamers of epithelial cell adhesion mol. (EpCAM) modified AuPt NPs were assembled with Co-MOF/Fe3O4/Ag NSs, which generated strong detection and reference signals at -0.7 V and 0.1 V, resp. The high affinity between EpCAM and aptamers induced the separation of AuPt NPs from Co-MOF/Fe3O4/Ag NSs, resulting in the decrease of detection signal at -0.7 V and unchanged reference signal at 0.1 V. A ratiometric electrochem. aptasensor was achieved for the sensitive and reliable quantification of EpCAM in the range from 100 pg/mL to 100 ng/mL. The limit of detection (LOD) was calculated to be 13.8 pg/mL for EpCAM. Plasmon-driven electrochem. oxidation enhancement principle provides the possibility for the design and fabrication of more strong and anti-interference electroactive plasmonic metal-Pt composite nanostructures for the electroanal. applications. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6COA of Formula: C4H10O3).
2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C4H10O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts