Feng, Yaoguang et al. published their research in Journal of Chemical Thermodynamics in 2022 | CAS: 57-55-6

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Quality Control of 1,2-Propanediol

Influence of high pressure on the solubility of ribavirin in six pure solvents from 283.15 to 323.15 K was written by Feng, Yaoguang;Hao, Hongxun;Tian, Beiqian;Chen, Kui;Wang, Na;Wang, Ting;Huang, Xin. And the article was included in Journal of Chemical Thermodynamics in 2022.Quality Control of 1,2-Propanediol This article mentions the following:

The solubility of ribavirin in six pure solvents was measured at 9.0 MPa and 0.1 MPa to evaluate the influence of high pressure on solubility at the temperature range from 283.15 K to 323.15 K. The results indicated that all the solubilities of ribavirin decreased slightly at 9.0 MPa compared with those at 0.1 MPa. Solvation free energy of ribavirin in six solvents under two pressures was calculated to explain the decrease of solubility under high pressure. Besides, the solubility of ribavirin increased with the rising temperature under both 0.1 MPa and 9.0 MPa. Furthermore, the exptl. solubility data under two pressures were correlated by the modified Apelblat equation and NRTL model. The average relative deviation value of the modified Apelblat equation is less than 3%, which can give better correlation results. Finally, the thermodn. properties of mixing and dissolution of ribavirin in six pure solvents under two pressures were also calculated based on the solubility exptl. data and the NRTL equation. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Quality Control of 1,2-Propanediol).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Quality Control of 1,2-Propanediol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts