Versatile one-pot synthesis of 3-alkenylcoumarins was written by Konigs, Pia;Neumann, Olivia;Hackeloeer, Kristina;Kataeva, Olga;Waldvogel, Siegfried R.. And the article was included in European Journal of Organic Chemistry in 2008.Electric Literature of C9H10O3 This article mentions the following:
A variety of 2-acyl-, 2-aroyl- and 2-formyl-substituted phenols are converted in a one-pot reaction with α,β-unsaturated carboxylic acid chlorides into the corresponding 3-alkenylcoumarins. Especially the labile 3-vinylcoumarins are readily available by the simple to perform protocol. If longer alkenyl chains are involved in position 3, small mols. with excellent organo gelating properties are established. The mode of action for such aggregates is confirmed by X-ray anal. of an analog. In the experiment, the researchers used many compounds, for example, 2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0Electric Literature of C9H10O3).
2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Electric Literature of C9H10O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts