Shipin Gongye Keji published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Synthetic Route of 526-98-7.
Gao, Ming published the artcileOptimization of fermentation conditions for two-step fermentation of vitamin C, Synthetic Route of 526-98-7, the publication is Shipin Gongye Keji (2012), 33(14), 235-238, database is CAplus.
The conversion process from L-sorbose to 2-keto-L-gulonic acid in vitamin C two-step fermentation was mixed culture fermentation by acid-producing strain (Gluconobacter oxydans) and companion bacterium (Bacillus subtilis). In order to promote the coordination between the two strains and make it reach the best state, the nutrient condition and the culture conditions were researched by orthogonal test and single factor experiment The result showed that the optimal conditions were as follows: 8% L-sorbose, 1.4% corn steep liquor, 1.2% urea, 0.5% CaCO3, 0.02% MgSO4, liquid volume in 100 mL flask with 10 mL, culture temperature 29°C, inoculation amount 15%. The yield of 2-KGA increased by 2.45% under the optimized culture medium conditions compared with the original medium. It reached the fermentation end after 60 h which was shortened by 16 h than before and the fermentation efficiency improved by 0.29 g/L·h.
Shipin Gongye Keji published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Synthetic Route of 526-98-7.
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