Baehr, Susanne published the artcileSelective Enzymatic Oxidation of Silanes to Silanols, Quality Control of 597-52-4, the publication is Angewandte Chemie, International Edition (2020), 59(36), 15507-15511, database is CAplus and MEDLINE.
Compared to the biol. world’s rich chem. for functionalizing carbon, enzymic transformations of the heavier homolog silicon are rare. We report that a wild-type cytochrome P 450 monooxygenase (P 450BM3 from Bacillus megaterium, CYP102A1) has promiscuous activity for oxidation of hydrosilanes to give silanols. Directed evolution was applied to enhance this non-native activity and create a highly efficient catalyst for selective silane oxidation under mild conditions with oxygen as the terminal oxidant. The evolved enzyme leaves C-H bonds present in the silane substrates untouched, and this biotransformation does not lead to disiloxane formation, a common problem in silanol syntheses. Computational studies reveal that catalysis proceeds through hydrogen atom abstraction followed by radical rebound, as observed in the native C-H hydroxylation mechanism of the P 450 enzyme. This enzymic silane oxidation extends nature’s impressive catalytic repertoire.
Angewandte Chemie, International Edition published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Quality Control of 597-52-4.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts