Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehydeOn September 2, 2013 ,《One-pot regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives – an easy access to “”nature-like molecules””; part XIII in the series: “”studies on novel synthetic methodologies””》 was published in Synlett. The article was written by Sashidhara, Koneni V.; Palnati, Gopala Reddy; Dodda, Ranga Prasad; Avula, Srinivasa Rao; Swami, Priyanka. The article contains the following contents:
A mild and highly practical regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives from 5-alkyl-4-hydroxyisophthalaldehydes with suitable substrates in acetic acid is reported. Further exploration of the mol. diversity of 2,3-dihydroquinazolinone is demonstrated by the synthesis of diverse pharmacol. relevant natural-product-like scaffolds. In the experiment, the researchers used 5-(tert-Butyl)-4-hydroxyisophthalaldehyde(cas: 153759-59-2Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehyde)
5-(tert-Butyl)-4-hydroxyisophthalaldehyde(cas: 153759-59-2) belongs to phenols.Name: 5-(tert-Butyl)-4-hydroxyisophthalaldehydeDeprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book).
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