In 2019,New Journal of Chemistry included an article by Anamika; Agrahari, Anand K.; Manar, Krishna K.; Yadav, Chote Lal; Tiwari, Vinod K.; Drew, Michael G. B.; Singh, Nanhai. Electric Literature of C7H9NO2. The article was titled 《Highly efficient structurally characterized novel precatalysts: di- and mononuclear heteroleptic Cu(I) dixanthate/xanthate-phosphine complexes for azide-alkyne cycloadditions》. The information in the text is summarized as follows:
Novel heteroleptic dinuclear [Cu2(L)(PPh3)4] (L = 2,6-pyridinedimethyldixanthate L1 1, 1,4-benznedimethyldixanthate L2 2, 1,4-cyclohexanedixanthate L3 3) and mononuclear [Cu(L4)(PPh3)2] 4, (L4 = piperonylxanthate) and [Cu(L5)(dppf)] (5) (L5 = methylxanthate, dppf = 1,1′-bis(diphenylphosphino)ferrocene) complexes were synthesized and characterized by elemental (C, H, and N) anal., high resolution mass spectrometry, and IR, UV-visible, 1H, 13C{1H} and 31P{1H} NMR spectroscopy. Single crystal x-ray diffraction revealed S,S-bidentate coordination of the dixanthate group in dinuclear 1-3 while 4 and 5 are mononuclear. 1-5 Adopt tetrahedral coordination geometry about the Cu atom. These precatalysts having two and one Cu(I) centers in a single mol. were applied in Cu catalyzed azide-alkyne cycloaddition (CuAAC) reactions for the synthesis of a variety of glycoconjugate triazoles using the Click approach. Particularly, the dinuclear catalyst 1, formed on the pyridyl linker based dixanthate ligand, displayed outstanding and reusable catalytic activity for this reaction. Full optimization of the reaction conditions demonstrated a Click catalytic system with low catalyst loading under mild reaction conditions.2,6-Pyridinedimethanol(cas: 1195-59-1Electric Literature of C7H9NO2) was used in this study.
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Electric Literature of C7H9NO2
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