Category: alcohols-buliding-blocksIn 2019 ,《O-H and (CO)N-H bond weakening by coordination to Fe(II)》 appeared in Dalton Transactions. The author of the article were Resa, Sandra; Millan, Alba; Fuentes, Noelia; Crovetto, Luis; Luisa Marcos, M.; Lezama, Luis; Choquesillo-Lazarte, Duane; Blanco, Victor; Campana, Araceli G.; Cardenas, Diego J.; Cuerva, Juan M.. The article conveys some information:
New N,N’-dimethyl-N,N’-bis(2-pyridylmethyl)-ethane-1,2-diamine derivatives bearing covalently linked OH and (CO)NH groups were synthesized. The coordination of those pendant hydroxyl/amide groups to a Fe(II) metal center is demonstrated both in solution, even in the presence of chloride as the counterion, and in solid state, by x-ray diffraction crystal structures. As a result of this coordination, the exptl. bond dissociation free energies (BDFE) of O-H and (CO)N-H bonds are remarkably diminished down to 76.0 and 80.5 kcal mol-1, resp., which is also in agreement with DFT-based theor. calculations These BDFE values are in the range of commonly used hydrogen-atom donor reagents. The strategy presented here allows an unequivocal evaluation of the influence of metal coordination in X-H bond weakening in organic solvents which could be easily extended to other metal centers. The experimental process involved the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Category: alcohols-buliding-blocks)
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Category: alcohols-buliding-blocks
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