《Cu-Catalyzed Dehydrogenative C-O Cyclization for the Synthesis of Furan-Fused Thienoacenes》 was written by Mitsudo, Koichi; Kobashi, Yoshiaki; Nakata, Kaito; Kurimoto, Yuji; Sato, Eisuke; Mandai, Hiroki; Suga, Seiji. Category: alcohols-buliding-blocksThis research focused onthiophenyl phenol copper catalyst dehydrogenative cyclization coupling; furan fused thienoacene preparation. The article conveys some information:
The first Cu-catalyzed dehydrogenative C-O cyclization for the synthesis of furan-fused thienoacenes is described. A variety of heteroacenes including a thieno[3,2-b]furan or a thieno[2,3-b]furan skeleton were synthesized by intramol. C-H/O-H coupling. The use of a mixed solvent of N-methyl-2-pyrrolidone, ethylene glycol monomethyl ether, and toluene was essential for suppressing side reactions and efficiently promoting the reaction. Double C-O cyclization was also conducted to afford highly π-expanded furan-fused thienoacenes. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxyphenylboronic acid(cas: 89466-08-0Category: alcohols-buliding-blocks)
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA), a synthetic molecule applied in RNA affinity chromatography, is able to form reversible covalent ester bonds with 1,2- or 1,3-cis-doils on the ribose ringCategory: alcohols-buliding-blocks
Referemce:
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