Safety of (3-Chlorophenyl)(phenyl)methanolOn March 27, 2013, Zhang, Wenxue; Dai, Yisi; Zhu, Haizhen; Zhang, Wei published an article in Tetrahedron Letters. The article was 《One-pot synthesis of indene derivatives by CF3SO3H-promoted reactions of benzylic alcohols and 1,3-dicarbonyl compounds》. The article mentions the following:
An efficient and convenient one-pot synthesis of indene derivatives was achieved in moderate to high yields by the CF3SO3H promoted coupling/cyclization reaction of benzylic alcs. and 1,3-dicarbonyls for the first time. For the reactions of methoxy- or methyl-substituted diarylmethanols with 1,3-dicarbonyls, 2 equiv of CF3SO3H was needed to reach the best results; but for the reactions of methoxy-substituted arylethanols with 1,3-dicarbonyls, 0.6 equiv of CF3SO3H at lower temperatures was capable of promoting the reaction finished. After reading the article, we found that the author used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Safety of (3-Chlorophenyl)(phenyl)methanol)
(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Safety of (3-Chlorophenyl)(phenyl)methanol The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts