Product Details of 1195-59-1In 2021 ,《Azine-N-oxides as effective controlling groups for Rh-catalyzed intermolecular alkyne hydroacylation》 was published in Chemical Science. The article was written by Moseley, Daniel F.; Kalepu, Jagadeesh; Willis, Michael C.. The article contains the following contents:
Azine N-oxide substituted aldehydes are used as highly effective substrates with good reactivity for intermol. hydroacylation of alkynes. Employing a Rh(I)-catalyst, a mild and scalable aldehyde C-H activation, that permits the coupling with unactivated terminal alkynes was achieved in good yields and with high regioselectivities (up to >20 : 1 l:b). Both substrates can tolerate a broad variety of functional groups. The reaction can also be applied to diazine aldehydes that contain a free N-lone pair. Conversion of the hydroacylation products to the corresponding azine, through a one-pot hydroacylation/deoxygenation sequence was also demonstrated. A one-pot hydroacylation/cyclization, using N-Boc propargylamine, addnl. leads to the synthesis of a bidentate pyrrolyl ligand. In the part of experimental materials, we found many familiar compounds, such as 2,6-Pyridinedimethanol(cas: 1195-59-1Product Details of 1195-59-1)
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Product Details of 1195-59-1
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