On August 1, 2022, Macia, Alba; Romero, Maria-Paz; Yuste, Silvia; Ludwig, Iziar; Pedret, Anna; Valls, Rosa Maria; Salamanca, Patricia; Sola, Rosa; Jose Motilva, Maria; Rubio, Laura published an article.HPLC of Formula: 621-37-4 The title of the article was Phenol metabolic fingerprint and selection of intake biomarkers after acute and sustained consumption of red-fleshed apple versus common apple in humans. The AppleCOR study. And the article contained the following:
The present study aimed to evaluate the metabolism and bioavailability of anthocyanins (ACN) and other phenolics from red-fleshed apple (RFA) and to define the intake biomarkers compared to common white-fleshed apple (WFA). Acute and sustained (6-wk) interventions were combined in a randomized, controlled and parallel study with 121 hypercholesterolemic subjects. Another arm consuming ACN-rich infusion from aronia fruit (ARO) provided matched content and profile of ACN. Plasma, urine and faeces samples were analyzed using UPLC-MS/MS. Results showed higher bioavailability of ACN after ARO compared to RFA, showing a clear apple matrix effect. The dihydrochalcone phloretin-2′-O-glucuronide was the most discriminant intake biomarker of both apples. The urinary peonidin-3-O-galactoside was a good biomarker after both ARO and RFA intakes, whereas peonidin-O-arabinoside was reported to be specific from ARO. The elucidation of the phenolic metabolism and the selection of intake biomarkers is a promising approach to relate phenolic compounds and human health. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).HPLC of Formula: 621-37-4
The Article related to malus phenol metabolic fingerprint biomarker, anthocyanins, intake biomarkers, metabolism, red-fleshed apple, uplc-ms/ms, Placeholder for records without volume info and other aspects.HPLC of Formula: 621-37-4
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