Puleo, Thomas R.; Klaus, Danielle R.; Bandar, Jeffrey S. published an article in 2021. The article was titled 《Nucleophilic C-H Etherification of Heteroarenes Enabled by Base-Catalyzed Halogen Transfer》, and you may find the article in Journal of the American Chemical Society.Application In Synthesis of 5-Hexen-1-ol The information in the text is summarized as follows:
A general protocol for the direct C-H etherification of N-heteroarenes is reported. Potassium tert-butoxide catalyzes halogen transfer from 2-halothiophenes to N-heteroarenes to form N-heteroaryl halide intermediates that undergo tandem base-promoted alc. substitution. Thus, the simple inclusion of inexpensive 2-halothiophenes enables regioselective oxidative coupling of alcs. with 1,3-azoles, pyridines, diazines, and polyazines under basic reaction conditions. The experimental part of the paper was very detailed, including the reaction process of 5-Hexen-1-ol(cas: 821-41-0Application In Synthesis of 5-Hexen-1-ol)
5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Application In Synthesis of 5-Hexen-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts