Rhodium-catalyzed asymmetric transfer hydrogenation of aryl alkyl ketones employing ligands derived from amino acids was written by Wettergren, Jenny;Zaitsev, Alexey B.;Adolfsson, Hans. And the article was included in Advanced Synthesis & Catalysis in 2007.HPLC of Formula: 171032-87-4 This article mentions the following:
The combination of (pentamethylcyclopentadienyl)rhodium dichloride dimer [{RhCl2Cp*}2] and pseudodipeptide ligands, formed from N-Boc protected amino acids and amino alcs., resulted in efficient and selective catalysts for the asym. transfer hydrogenation of ketones in 2-propanol. A number of different secondary alcs., e.g., I, were obtained in high yields and in excellent enantioselectivity using these in situ formed catalysts. Deuterium-labeling experiments showed that the hydride transfer reaction occurs via the monohydridic route. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4HPLC of Formula: 171032-87-4).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 171032-87-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts